Biological Gerontology .com
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What is Biogerontology?

Biogerontology is the scientific investigation into how and why we age on the molecular level, the organismic level, evolutionary level, and all those in between. This discipline seeks to understand why underfed animals live longer (as they do with caloric restriction), how free radicals might take years off our lives, where telomeres come into play with aging cells and aging people, and why having offspring later in life increases lifespan over many generations. Understanding the biological basis of aging is the first step towards slowing the aging process down, and maybe someday reversing the process. Today we are making steady progress in extending the lifespan of animals using a variety of methods, and more likely than not are going to someday apply these same techniques to ourselves to increase the average and maxmimum lifespan of the human species. Biogerontology is the field which seeks to develop a biological understanding of the processes of aging, and is the field in which we will apply these findings to increase the length and vitality of our lives.


On the "Anti-Aging" Fad

The terms "anti-aging, "life-extension," "pro-longevity," or "longevity-enhancing" are widely applied to various products, medicines and therapies. Within the realm of scientific investigation, these terms are perhaps best defined as procedures or regimens that have been repeatedly proven to increase maximum or average longevity in large populations of mammals. Unfortunately, bevies of merchants that sell products using these terms don't share such a definition. At best, individuals or organizations claiming they possess anything scientifically worthy of the term "anti-aging" are at best self-deluded, or at worst lying swindlers. To date, nothing aside from caloric restriction even seems to warrant these labels. This may appear a small point to make, but many hold false beliefs that experiments have established antioxidants, natural peptides, telomerase, etc. to have an effect on the aging process and longevity. If this were in fact the case, these would mark a spectacular milestone in human history.


Future of Biogerontology

Despite the ubiquity of fallicious products, the fact that so much is unknown about aging and senescence makes biogerontology an exciting nascent field. The future discovery and in-depth characterization of the specific mechanisms that underly these processes could very well lend to bona fide interventions, and the fact that so many scientists (and private and governmental investors) are now taking more seriously these possibilities and investing their time and interest into biogerontological research might entail the field coming to fruition in the near future.
Contents
What is biogerontology?
Why do we age?
Why is biogerontology important?
Mitochondria and aging
Free radicals and aging
Stem cells and aging links
Telomeres and aging links

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Old Articles
Deprenyl and Longevity
Ependymin and CereMedix
Reliability Theory
Polypill for Heart Disease
Telomerase as RNAi Cancer Target
Atherosclerosis and Stem Cells
Old Evol-Biology Claimed New
Stem Cell Reprogramming
Current Stem Cell Research
AGEs and Anti-Crosslink Drugs
RNAi Interference
Free Radicals
Synthetic Antioxidants
Daf-2 and C. Elegans Lifespan