| |
USC researchers have found that synthetic antioxidant compounds that mimic the activity of superoxide dismutase and catalase, made by the company eukarion (alas, not publicly traded), delay memory loss in mice. It is thought that oxidative stress plays a central role in many facets of aging, and thus unique antioxidant compounds such as these hold much promise for increasing health and longevity. The Buck Institute has found previously that the reduced longevity of transgenic mice lacking superoxide dismutase is reversed when eukarion compounds are adminstered to them. They additionally found that the onset of neuropathologic disorders was attenuated with the administration of the compounds. With wildtype C. elegans, Buck researchers were able to increase lifespan approximately 50%. EurekAlert Article
Recent Related References:
- Blueberry-enriched diet protects rat heart from ischemic damage. Ahmet I, Spangler E, Shukitt-Hale B et al. PLoS One. 2009 Jun 18. PMID: 19536295
- Cognitive and behavioral assessment in dogs and pet food market applications. Zicker SC. Prog Neuropsychopharmacol Biol Psychiatry. 2005 Mar. PMID: 15795054
- [DNA protective activity of natural and synthetic antioxidants] Zinov'eva VN, Spasov AA. Biomed Khim. 2004 May-Jun. PMID: 15354534
- Protective effects of topical antioxidants in humans. Dreher F, Maibach H. Curr Probl Dermatol. 2001. PMID: 11225195
- Neurobehavioral aspects of antioxidants in aging. Cantuti-Castelvetri I, Shukitt-Hale B, Joseph JA. Int J Dev Neurosci. 2000 Jul-Aug. PMID: 10817921
- [Free-radical perodixative reactions in the acute period of craniocerebral trauma] Pedachenko EG, Sutkovoĭ DA, Malyshev OB et al. Lik Sprava. 1999 Jan-Feb. PMID: 10423998
- Adequate iron stores and the 'Nil nocere' principle. Hollán S, Johansen KS. Haematologia (Budap). 1993. PMID: 8244202
- [Effect of antioxidants on the synthesis of prostaglandins, prostacyclin and thromboxane in different layers of the kidneys of old rats] Efendiev AM, Pomoĭnetskiĭ VD, Smirnov LD et al. Farmakol Toksikol. 1986 May-Jun. PMID: 3522269
- Aspects of free radical reactions in biological systems: aging. Leibovitz BE, Siegel BV. J Gerontol. 1980 Jan. PMID: 6243146
by Chris Smelick at biologicalgerontology.com
copyright 2003-2009
|
|
|
